Vitamin K2 Menatetrenone
Vitamin K2 Menatetrenone
Vitamin K2 menatetrenone (MK-4), a form of vitamin K2 made in the body from phylloquinone (vitamin K1) and distinct from the menaquinones made by probiotic bacteria.
Available science indicates that vitamin K2 - and especially menatetrenone - is superior to Vitamin K1 in maintaining the health of the bones and vascular system.
Clinical trials have proven that high-dose vitamin K2 does not cause excessive or abnormal blood clotting, although it will interfere with "blood thinning" medications.
90 Vegi-Caps
Supplement Facts
- Serving Size: 1 Capsule %DRI
- Menatetrenone (MK-4) …. 15 mg 12500%
*Dietary Reference Intake not established.
Other ingredients: rice flour. Capsule: vegetarian (hydroxypropylmethylcellulose).
Relentless Improvement guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, nuts, dairy, soy, eggs, fish, or shellfish.
Vitamin K2 Menatetrenone Suggested Use
Suggested Use
Take one to three capsules daily with fat-containing meals, or as directed by a qualified health consultant.
K2 Menatetrenone Cautions
Clinical trials have documented that menatetrenone does not induce hemostatic activation. However, it will interfere with the activity warfarin (Coumadin®) and possibly other anticoagulant ("blood thinning") medications. Patients prescribed anticoagulants must not take this supplement.
Key Ingredient: Vitamin K2 Menatetrenone
STORE IN A COOL DARK PLACE. HARMLESS CLUMPING MAY OCCUR AT TEMPERATURES EXCEEDING 35OC (95 degrees F)
Vitamin K2 Menatetrenone Research
K2-The First Bone-Building Supplement!
Vitamin K is an essential nutrient, best known for its role in blood clotting. Plants make one form of vitamin K (phylloquinone, or vitamin K1) for their use. But your body doesn't use all of the K1 in your diet "as is." Instead, the body converts some of this plant form of the vitamin into a different vitamin K molecule: Menatetrenone, or MK-4, a form of vitamin K2. Tissues vary in their vitamin K needs, and it's become clear that some tissues have a specific need for Menatetrenone, which is not met by phylloquinone. For some purposes (like blood clotting), phylloquinone works fine; but extensive evidence shows that Menatetrenone has unique effects on bone health not shared by phylloquinone.
Over the course of the last decade, at least sixteen clinical trials have been performed using Menatetrenone, and every single one has found that K2 supplements protect bone health. Menatetrenone not only slows, halts, or even reverses loss of bone mass: it dramatically reduces your risk of suffering a fracture.
Menatetrenone's health benefits extend well beyond the skeletal system. Emerging science is now documenting the role of vitamin K - and specifically of Menatetrenone - in protecting our cardiovascular health, and the health of that all-important organ, the brain.
References
- Orimo H, Shiraki M, Tomita A, Morii H, Fujita T, Ohata M. "Effects of menatetrenone on the bone and calcium metabolism in osteoporosis: a double-blind placebo-controlled trial." J Bone Miner Metab 1998; 16(2): 106-12
- Iwamoto J, Takeda T, Ichimura S. "Effect of menatetrenone on bone mineral density and incidence of vertebral fractures in postmenopausal women with osteoporosis: a comparison with the effect of etidronate." J Orthop Sci. 2001; 6(6): 487-92.
- Shiraki M, Shiraki Y, Aoki C, Miura M. "Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis." J Bone Miner Res. 2000 Mar; 15(3): 515-21
- Geleijnse JM, Vermeer C, Jurgers LJ, Grobbee DE, Pols HA, Witteman JC. "Inverse association of dietary vitamin K-2 intake with cardiac eventsand aortic atherosclerosis: the Rotterdam Study." Thromb Haem. 2001 Jul; 85(Suppl): AbsP473.
- Allison AC. "The possible role of vitamin K deficiency in the pathogenesis of Alzheimer's disease and in augmenting brain damage associated with cardiovascular disease." Med Hypotheses. 2001 Aug; 57(2): 151-5.